SCHEMBL5497740

SCHEMBL5497740

CCOC(=O)CN[C@@H](Cc1ccccc1)C(=O)OS(=O)(=O)CCN

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR142 Q7Z601 1/20 0.45
HPRT1 P00492 1/20 0.43
PPID Q08752 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MMP8 P22894 1/20 0.40
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
POLB P06746 3/20 0.38
LTA4H P09960 2/20 0.38
CA1 P00915 1/20 0.38
BACE1 P56817 1/20 0.37
EGFR P00533 1/20 0.37
MME P08473 1/20 0.37
EPHX2 P34913 1/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17287421 0.82 PPID (0.54) GPR142HPRT1PPIDMEN1KMT2A
SCHEMBL2896038 0.81 MEN1 (0.57) GPR142PPIDMEN1KMT2AMMP8
SCHEMBL2896037 0.81 MEN1 (0.57) GPR142PPIDMEN1KMT2AMMP8
SCHEMBL10073607 0.79 PPID (0.54) GPR142PPIDMEN1KMT2AMMP8
SCHEMBL7428720 0.76 ITGA4 (0.59) GPR142PPIDMEN1KMT2AMMP8
SCHEMBL7428724 0.76 ITGA4 (0.59) GPR142PPIDMEN1KMT2AMMP8
SCHEMBL5497742 0.76 GPR142 (0.49) GPR142PPIDMMP8POLBLTA4H
SCHEMBL5501203 0.74 ALPI (0.51) LTA4H
SCHEMBL9554934 0.74 PPID (0.56) GPR142PPIDMMP8LTA4HEPHX2
SCHEMBL15722181 0.73 PPID (0.47) GPR142HPRT1PPIDMMP8LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189708-B2 Topical composition for skin KAO CORPORATION (JP) 2007-03-13 US disclosed
EP-1090625-B1 Topical composition for the skin and use thereof KAO CORP (JP) 2004-12-22 EP disclosed
US-20030087833-A1 Topical composition for skin KAO CORPORATION (JP) 2003-05-08 US disclosed
US-6489291-B1 Topical composition for skin KAO CORPORATION (JP) 2002-12-03 US disclosed
EP-1090625-A2 Topical composition for the skin and use thereof Kao Corporation (JP) 2001-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087833-A1 Topical composition for skin CUTA, SLC38A7, CCR8 GPR142 1372/4885HPRT1 2563/4885PPID 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.