Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870028 | 0.87 | HRH3 (0.30) | HRH3CPN1CPB2 | |
| SCHEMBL31458641 | 0.81 | GNAO1 (0.36) | HRH3CPN1CPB2CHRM1CHRM3 | |
| SCHEMBL9450351 | 0.78 | METAP1 (0.36) | — | |
| SCHEMBL12822223 | 0.77 | — | — | |
| SCHEMBL6877804 | 0.76 | METAP1 (0.39) | — | |
| SCHEMBL31458643 | 0.72 | GNAO1 (0.34) | HRH3CPN1CPB2CHRM1CHRM3 | |
| SCHEMBL11302107 | 0.72 | DPP4 (0.41) | HRH3CPN1CPB2CHRM1CHRM3 | |
| SCHEMBL357186 | 0.69 | — | — | |
| SCHEMBL60981 | 0.69 | — | — | |
| SCHEMBL104444 | 0.69 | GNAO1 (0.37) | HRH3CPN1CPB2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173136-B2 | 3-Cyano-quinoline derivatives | ASTRAZENECA AB (SE) | 2007-02-06 | — | — | US | disclosed |
| US-20050282856-A1 | 3-Cyano-quinoline derivatives | ASTRAZENECA AB (SE) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282856-A1 | 3-Cyano-quinoline derivatives | MKI67, CCNA1, CCNT1 | HRH3 961/4885CPN1 227/4885CPB2 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.