Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915366 | 0.88 | ALDH1A1 (0.36) | IMPDH2XDHMAPK1P2RX7 | |
| SCHEMBL917251 | 0.86 | ALDH1A1 (0.34) | IMPDH2XDHMAPK1P2RX7 | |
| SCHEMBL916264 | 0.83 | ALDH1A1 (0.34) | XDHMAPK1P2RX7 | |
| SCHEMBL916462 | 0.83 | LMNA (0.36) | IMPDH2XDHP2RX7 | |
| SCHEMBL711086 | 0.83 | KMT2A (0.38) | PGRNR3C1NR3C2ARBRD4 | |
| SCHEMBL916474 | 0.82 | IMPDH2 (0.40) | ARIMPDH2XDH | |
| SCHEMBL916794 | 0.81 | CYP1A2 (0.41) | MAPK1P2RX7 | |
| SCHEMBL709121 | 0.80 | P2RX7 (0.44) | MAPK1P2RX7 | |
| SCHEMBL917250 | 0.79 | ALDH1A1 (0.37) | XDHMAPK1 | |
| SCHEMBL916614 | 0.74 | GAA (0.36) | BRD4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742912-A1 | NOVEL ANDROGENS | N.V. Organon (NL) | 2007-01-17 | — | — | EP | claimed |
| WO-2005102998-A1 | NOVEL ANDROGENS | N.V. ORGANON (NL) | 2005-11-03 | — | — | WO | claimed |