Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177741 | 0.77 | AR (0.51) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL31415661 | 0.74 | GAA (0.47) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL28625665 | 0.70 | AR (0.61) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL5498981 | 0.70 | AR (0.50) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL5507928 | 0.70 | POLB (0.50) | ARPOLBGAAEZH2TSHR | |
| SCHEMBL18181841 | 0.69 | AR (0.60) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL7054403 | 0.69 | GAA (0.64) | ARPOLBGAASLC22A12TSHR | |
| SCHEMBL24540615 | 0.68 | PIN1 (0.46) | ARPOLBGAASLC22A12LMNA | |
| SCHEMBL7025384 | 0.68 | SLC22A12 (0.41) | ARPOLBGAASLC22A12EZH2 | |
| SCHEMBL4175396 | 0.68 | SLC22A12 (0.39) | ARSLC22A12TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |