Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652741 | 0.81 | L3MBTL1 (0.46) | MAPTKMT2AMEN1ALOX12SIGMAR1 | |
| SCHEMBL16302331 | 0.81 | CYP1A2 (0.42) | MAPTKMT2AMEN1ALOX12L3MBTL1 | |
| SCHEMBL6076744 | 0.81 | HPGD (0.47) | MAPTKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL2178103 | 0.77 | CYP3A4 (0.48) | MAPTKMT2AMEN1SIGMAR1CYP3A4 | |
| SCHEMBL8131169 | 0.75 | SIGMAR1 (0.48) | MAPTKMT2AMEN1SIGMAR1CYP3A4 | |
| SCHEMBL10439288 | 0.74 | HRAS (0.41) | MAPTKMT2AMEN1ALOX12CYP3A4 | |
| SCHEMBL206646 | 0.74 | HRAS (0.65) | MAPTKMT2AMEN1CYP3A4KDM4E | |
| Dimethylamine SCHEMBL28814481 | 0.73 | CYP3A4 (0.50) | MAPTKMT2AMEN1SIGMAR1CYP3A4 | |
| SCHEMBL5179520 | 0.73 | CYP3A4 (0.45) | MAPTKMT2AMEN1SIGMAR1CYP3A4 | |
| SCHEMBL5506614 | 0.73 | KDM4E (0.45) | MAPTKMT2AMEN1SIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107200707-A | A kind of Mo Fanselin preparation method | 河北科技大学 | 2017-09-26 | — | — | CN | claimed |
| CN-111517966-A | Method for synthesizing p-isobutoxybenzylamine | 杭州益至生物科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-109705848-A | One-dimensional organic semiconductor nanowires circle and its preparation method and application | 中国科学院化学研究所 | 2019-05-03 | — | — | CN | disclosed |
| CN-108250087-A | A kind of synthetic method of 4- isobutoxies benzylamine | 常州大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-104961672-B | A kind of synthetic method of the tartrate of N (4 luorobenzyl) N (base of 1 methyl piperidine 4) N ' (4 isobutoxy benzyl) urea | 沈阳药科大学 | 2017-10-20 | — | — | CN | disclosed |
| EP-1794126-A1 | SYNTHESIS OF N-(4-FLUOROBENZYL)-N-(1-METHYLPIPERIDIN-4-YL)-N'-(4-(2-METHYLPROPYLOXY)PHENYLMETHYL)CARBAMIDE AND ITS TARTRATE SALT AND CRYSTALLINE FORMS | Acadia Pharmaceuticals Inc. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037043-A1 | SYNTHESIS OF N-(4-FLUOROBENZYL)-N-(1-METHYLPIPERIDIN-4-YL)-N'-(4-(2-METHYLPROPYLOXY)PHENYLMETHYL)CARBAMIDE AND ITS TARTRATE SALT AND CRYSTALLINE FORMS | ACADIA PHARMACEUTICALS INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |