Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225776 | 0.80 | HRH3 (0.54) | SIGMAR1ALDH1A1MAPTHRH3 | |
| SCHEMBL643893 | 0.80 | HRH3 (0.48) | SIGMAR1ALDH1A1MAPTHRH3 | |
| SCHEMBL11833413 | 0.79 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1MAPTHRH3 | |
| SCHEMBL5499433 | 0.78 | HPGD (0.35) | ALDH1A1HPGDNPC1 | |
| SCHEMBL5499197 | 0.77 | CXCR4 (0.48) | SIGMAR1KDM1ACHRM2CHRM4CHRM5 | |
| SCHEMBL4526651 | 0.77 | KEAP1 (0.52) | PAOXSIGMAR1USP2ALDH1A1HPGD | |
| SCHEMBL3952508 | 0.76 | PAOX (0.47) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6663287 | 0.75 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20234244 | 0.75 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6657767 | 0.75 | PAOX (0.54) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005470-B1 | OXINDOLYLQUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2007-08-01 | — | — | EP | disclosed |