Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23654217 | 0.86 | TAAR1 (0.54) | MEN1KMT2AHDAC1HDAC8TAAR1 | |
| SCHEMBL3710360 | 0.85 | HDAC1 (0.56) | MEN1KMT2AHDAC1HDAC8TAAR1 | |
| SCHEMBL5503261 | 0.83 | MEN1 (0.47) | KDM4EMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL5503782 | 0.82 | NOS1 (0.50) | KDM4ETAAR1ADRB2ADORA3CHRM1 | |
| SCHEMBL29499605 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL25233635 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL9989291 | 0.80 | TAAR1 (0.61) | KDM4EMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL25630655 | 0.80 | KDM4E (0.53) | KDM4EMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL10623816 | 0.79 | TAAR1 (0.53) | KDM4EMEN1KMT2ATDP1HDAC1 | |
| SCHEMBL10452195 | 0.79 | ADRB2 (0.68) | KDM4EMEN1KMT2ATDP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |