Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877056 | 0.87 | MIF (0.47) | CTSKCTSSMAPTCA1CA2 | |
| SCHEMBL391359 | 0.86 | TRPA1 (0.47) | CTSKCTSSMAPTTRPA1CTSL | |
| SCHEMBL7878973 | 0.86 | CTSK (0.40) | CTSKCTSSMAPTCA1CA2 | |
| SCHEMBL1194009 | 0.85 | CTSK (0.55) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL6609045 | 0.85 | CTSK (0.55) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL1193789 | 0.85 | CTSK (0.55) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL6608688 | 0.83 | CYP17A1 (0.44) | CTSKCTSSMAPTCA1CA2 | |
| SCHEMBL18989589 | 0.75 | CTSK (0.51) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL18989601 | 0.75 | CTSK (0.51) | CTSKCTSSMAPTATMCTSL | |
| SCHEMBL6608864 | 0.75 | RAB9A (0.49) | CTSKCTSSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748985-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | Takeda Pharmaceutical Company Limited (JP) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005113504-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-01 | — | — | WO | disclosed |