Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505363 | 0.76 | HRH3 (0.36) | — | |
| SCHEMBL5505366 | 0.76 | HRH3 (0.36) | — | |
| SCHEMBL5500648 | 0.75 | SMN1; SMN2 (0.49) | KMT2AALDH1A1 | |
| SCHEMBL5501533 | 0.74 | HRH3 (0.33) | LMNA | |
| SCHEMBL5507425 | 0.73 | HPGD (0.43) | CYP1A2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5505485 | 0.72 | CYP1A2 (0.38) | CYP1A2ALDH1A1ADRA2A | |
| SCHEMBL5502129 | 0.69 | SIGMAR1 (0.41) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL21637768 | 0.69 | CYP1A2 (0.69) | CYP1A2ALDH1A1ADRA2A | |
| SCHEMBL5504819 | 0.68 | NSD2 (0.36) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL26171317 | 0.68 | SMN1; SMN2 (0.41) | LMNAMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |