Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500662 | 1.00 | F10 (0.33) | F10MEN1ALDH1A1KMT2A | |
| SCHEMBL5502921 | 0.83 | GRM2 (0.35) | F10 | |
| SCHEMBL4061678 | 0.80 | F10 (0.30) | F10 | |
| SCHEMBL5501727 | 0.79 | P2RX7 (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL5500515 | 0.78 | P2RX7 (0.42) | KMT2A | |
| SCHEMBL5505772 | 0.76 | KMT2A (0.35) | ALDH1A1KMT2A | |
| SCHEMBL5504186 | 0.75 | F10 (0.35) | F10 | |
| SCHEMBL5500083 | 0.73 | HCRTR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5505760 | 0.72 | HCRTR1 (0.33) | — | |
| SCHEMBL4181628 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807072-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006049952-A1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2006-05-11 | — | — | WO | disclosed |