SCHEMBL55010

SCHEMBL55010

N#Cc1c(S)c2c(c(S)c1C#N)C(=O)c1ccccc1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
USP8 P40818 4/20 0.44
USP7 Q93009 3/20 0.44
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
CDC25B P30305 1/20 0.42
MAOA P21397 5/20 0.42
MAPT P10636 4/20 0.42
ADORA2A P29274 2/20 0.42
PIM1 P11309 2/20 0.42
FGR P09769 1/20 0.42
CSNK1A1 P48729 1/20 0.42
CSNK1D P48730 1/20 0.42
DYRK1A Q13627 1/20 0.42
HIPK2 Q9H2X6 1/20 0.42
CSNK1G1 Q9HCP0 1/20 0.42
USP47 Q96K76 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295307 0.81 ALDH1A1 (0.49) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
Methane SCHEMBL28696439 0.79 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
Methane SCHEMBL4141657 0.79 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL27362730 0.79 MAOA (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL29240248 0.78 MEN1 (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL1995922 0.76 ADORA2A (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL30085023 0.76 ADORA2A (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL9618328 0.76 MEN1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL12114202 0.76 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19USP8
SCHEMBL615483 0.72 USP8 (0.53) ALDH1A1CYP1A2CYP2C9CYP2C19USP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262414-A Acrylic acid morpholide derivatives SHELL RESEARCH LIMITED (GB) 1993-11-16 US claimed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 CN disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
CN-115846179-A Method for producing an antifouling coating system 汉伯公司 2023-03-28 CN disclosed
CN-112236486-B Method for producing an antifouling coating system 汉伯公司 2022-12-13 CN disclosed
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2021-11-16 US disclosed
CN-108291055-B Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-07-06 CN disclosed
US-10988611-B2 Crosslinked polyvinylpyrrolidone compositions ISP INVESTMENTS LLC (US) 2021-04-27 US disclosed
CN-112707851-A Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-04-27 CN disclosed
CN-112236486-A Method for producing an antifouling coating system 汉伯公司 2021-01-15 CN disclosed
US-4420486-A Benzoxazolone derivatives, processes for preparation thereof and compositions containing them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-12-13 US disclosed
US-4391804-A Imidazole derivatives and fungicidal composition containing the same HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1983-07-05 US disclosed
US-4350701-A 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed
EP-0057440-A1 Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them SANKYO COMPANY LIMITED (JP) 1982-08-11 EP disclosed
US-4323680-A 4-Aminoquinazoline compounds useful as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1982-04-06 US disclosed
US-4304778-A 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties SANKYO COMPANY LIMITED (JP) 1981-12-08 US disclosed
US-4279908-A Pyridazine derivatives and their use as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1981-07-21 US disclosed
US-4213987-A 4-AMINOQUINAZOLINES SANKYO COMPANY LIMITED (JP) 1980-07-22 US disclosed
US-4174393-A INSECTICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1979-11-13 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT ALDH1A1 2873/4885CYP1A2 3559/4885CYP2C9 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.