Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058133 | 0.93 | OPRM1 (0.56) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL3667052 | 0.93 | FKBP4 (0.58) | KMT2AFKBP4TACR1OPRM1OPRD1 | |
| SCHEMBL7076149 | 0.91 | FKBP4 (0.56) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL3277774 | 0.90 | FKBP4 (0.57) | KMT2AFKBP4TACR1OPRM1OPRD1 | |
| SCHEMBL5501048 | 0.87 | TACR1 (0.47) | KMT2AFKBP4TACR1PSMB9 | |
| SCHEMBL7048929 | 0.85 | TACR1 (0.51) | KMT2AFKBP4TACR1PSMB9 | |
| SCHEMBL11103910 | 0.85 | FKBP4 (0.58) | KMT2AFKBP4TACR1OPRM1OPRD1 | |
| SCHEMBL1295326 | 0.85 | F2 (0.54) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL27843840 | 0.85 | F2 (0.54) | FKBP4TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL14027241 | 0.83 | FKBP4 (0.65) | FKBP4TACR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042245-A1 | NEUROTROPHIC BICYCLIC DIAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |