SCHEMBL5501348

SCHEMBL5501348

Cc1ccccc1N(OB(O)c1ccccc1)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.37
PCSK9 Q8NBP7 2/20 0.35
TRPV6 Q9H1D0 2/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
ENPP2 Q13822 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
KMT2A Q03164 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
LMNA P02545 3/20 0.32
TEAD1 P28347 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14677580 0.75 TRPV6 (0.42) PCSK9TRPV6CA4CA6CA5A
SCHEMBL27871 0.72 TRPV6 (0.44) PCSK9TRPV6CA4CA6CA5A
SCHEMBL29234963 0.71 ORAI1 (0.32) PCSK9TRPV6CA4CA6CA5A
SCHEMBL969625 0.68 ENPP2 (0.39) PCSK9TRPV6CA4CA6CA5A
SCHEMBL28824873 0.68 PCSK9 (0.41) PCSK9TRPV6CA4CA6CA5A
SCHEMBL29216156 0.67 TRPV6 (0.38) PCSK9TRPV6CA4CA6CA5A
SCHEMBL9431996 0.66 TSHR (0.36) TRPM8CA4MEN1TP53KMT2A
SCHEMBL30528208 0.66 TRPM8 (0.41) TRPM8MEN1TP53KMT2ASIGMAR1
SCHEMBL21177785 0.66 MEN1 (0.37) PCSK9TRPV6CA4CA6CA5A
SCHEMBL56106 0.65 TRPV6 (0.50) PCSK9TRPV6CA4CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1807482-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY (US) 2007-07-18 EP disclosed
WO-2006049860-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY (US) 2006-05-11 WO disclosed