Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177785 | 0.90 | MEN1 (0.37) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL28824873 | 0.77 | PCSK9 (0.41) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL6470522 | 0.76 | CA4 (0.42) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL14677580 | 0.76 | TRPV6 (0.42) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL29216156 | 0.75 | TRPV6 (0.38) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL691860 | 0.73 | ENPP2 (0.50) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL1570273 | 0.73 | TRPV6 (0.44) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL5501348 | 0.72 | TRPM8 (0.37) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL1808334 | 0.72 | ORAI1 (0.39) | TRPV6ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL1848691 | 0.72 | TRPV6 (0.63) | TRPV6ENPP2ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004194-B | Circular polarization luminescent organic micro-nano crystal material and preparation method and application thereof | 中国科学院化学研究所 | 2022-12-09 | — | — | CN | claimed |
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | claimed |
| US-20230390319-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-12-07 | — | — | US | disclosed |
| CN-114516832-B | Tubulin inhibitor and preparation method and application thereof | 成都贝诺科成生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4233864-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT | Ajou University Industry-Academic Cooperation Foundation (KR) | 2023-08-30 | — | — | EP | disclosed |
| CN-114656397-B | Compound, two-dimensional organic crystal containing compound, preparation method and application | 中国科学院化学研究所 | 2023-07-25 | — | — | CN | disclosed |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-15 | — | — | US | disclosed |
| CN-113004194-B | Circular polarization luminescent organic micro-nano crystal material and preparation method and application thereof | 中国科学院化学研究所 | 2022-12-09 | — | — | CN | disclosed |
| CN-115385956-A | Biaryl diphosphine ligands and transition metal complexes thereof | 东莞市均成高新材料有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-114656397-A | Compound, two-dimensional organic crystal containing compound, preparation method and application | 中国科学院化学研究所 | 2022-06-24 | — | — | CN | disclosed |
| CN-113582940-B | Lipid drop specific fluorescent probe and synthetic method thereof | 四川大学华西医院 | 2022-05-20 | — | — | CN | disclosed |
| WO-2006058016-A2 | ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE AND SEROTONIN | AMR TECHNOLOGY, INC. (US) | 2006-06-01 | — | — | WO | disclosed |
| WO-2006033795-A2 | SUBSTITUTED PYRAZOLO [1, 5-A] PYRIMIDINES FOR INHIBITING ABNORMAL CELL GROWTH | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006033796-A1 | SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME | WYETH (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |
| EP-1294823-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG Chem, Ltd. (KR) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002088274-A1 | DOUBLE-SPIRO ORGANIC COMPOUNDS AND ELECTROLUMINESCENT DEVICES | LG CHEM, LTD. (KR) | 2002-11-07 | — | — | WO | disclosed |
| US-5512246-A | Method and means for detecting polyhydroxyl compounds | Russell, Anthony P. (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0502955-A1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS. | DU PONT (US) | 1992-09-16 | — | — | EP | disclosed |
| WO-1991008198-A1 | FLUORINATED SULFONES/KETONES FOR NONLINEAR OPTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230390319-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT | STING1, IRF3, IFNG | TRPV6 2903/4885ENPP2 1063/4885ORAI1 1719/4885 |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CDC37, ILK, PTMS | TRPV6 4224/4885ENPP2 3237/4885ORAI1 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.