Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412404 | 0.87 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL5518455 | 0.84 | MAPT (0.56) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL14886127 | 0.81 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL16294684 | 0.80 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL5523242 | 0.78 | KMT2A (0.51) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL14099552 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL5514795 | 0.75 | L3MBTL1 (0.57) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL5996870 | 0.74 | SHMT2 (0.51) | ALDH1A1LMNAMAPTGAATSHR | |
| SCHEMBL3568122 | 0.74 | TUBB4A (0.60) | LMNAGAATSHRTRPV1ALOX15 | |
| SCHEMBL2711213 | 0.74 | MAPT (0.68) | ALDH1A1MAPTGAATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855548-A2 | MOLECULES COMPRISING LINKED ORGANIC MOIETIES AS FLAVOR MODIFIERS FOR COMESTIBLES COMPOSITIONS | Senomyx, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| US-20060257543-A1 | Molecules comprising linked organic moieties as flavor modifiers for comestible compositions | SENOMYX, INC. | 2006-11-16 | — | — | US | disclosed |
| WO-2006084184-A2 | MOLECULES COMPRISING LINKED ORGANIC MOIETIES AS FLAVOR MODIFIERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |