Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495851 | 0.86 | KDM4A (0.43) | KDM4ANAAAPOLBCNR1LMNA | |
| SCHEMBL5494963 | 0.81 | KDM4A (0.43) | KDM4ANAAAPOLBCNR1LMNA | |
| SCHEMBL5497841 | 0.81 | KDM4A (0.43) | KDM4ANAAAPOLBCNR1LMNA | |
| SCHEMBL5493849 | 0.77 | GRIA1 (0.48) | — | |
| SCHEMBL17234594 | 0.69 | BCAT2 (0.49) | POLB | |
| SCHEMBL5495822 | 0.68 | KDM4A (0.41) | KDM4ANAAAPOLB | |
| SCHEMBL988168 | 0.68 | NAAA (0.59) | KDM4ANAAAPOLBLMNAPAX8 | |
| SCHEMBL5487144 | 0.67 | CHRNB2 (0.55) | — | |
| SCHEMBL5487146 | 0.67 | CHRNB2 (0.55) | — | |
| SCHEMBL5494078 | 0.67 | CHRNB2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753782-A1 | MEDIATORS OF REVERSE CHOLESTEROL TRANSPORT FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | AVANIR PHARMACEUTICALS (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005123770-A1 | MEDIATORS OF REVERSE CHOLESTEROL TRANSPORT FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA | AVANIR PHARMACEUTICALS (US) | 2005-12-29 | — | — | WO | disclosed |