Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506694 | 0.98 | PAOX (0.36) | PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL5501800 | 0.90 | ALDH1A1 (0.39) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5504004 | 0.89 | HRH3 (0.41) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5504843 | 0.87 | SIGMAR1 (0.44) | POLBHRH3SIGMAR1KDM1A | |
| SCHEMBL5502187 | 0.87 | HRH3 (0.44) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5502432 | 0.87 | HRH3 (0.41) | ALDH1A1POLBTHRBSMN1; SMN2HRH3 | |
| SCHEMBL5507633 | 0.84 | KDM4E (0.45) | PAOXALDH1A1POLBSMN1; SMN2HRH3 | |
| SCHEMBL5505456 | 0.83 | CSNK2A2 (0.33) | PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL5508190 | 0.81 | HRH3 (0.44) | HRH3MAOBHTR7 | |
| SCHEMBL5506691 | 0.80 | ALDH1A1 (0.32) | PAOXCSNK2A2CSNK2BCSNK2A1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |