Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501800 | 0.89 | ALDH1A1 (0.39) | KDM4ELMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12522670 | 0.88 | KDM4E (0.54) | KDM4ELMNARAB9AKEAP1SMN1; SMN2 | |
| SCHEMBL5502432 | 0.86 | HRH3 (0.41) | KDM4ELMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5506694 | 0.86 | PAOX (0.36) | KDM4ELMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5504004 | 0.84 | HRH3 (0.41) | LMNASMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL5505457 | 0.84 | PAOX (0.37) | SMN1; SMN2ALDH1A1SIGMAR1HRH3POLB | |
| SCHEMBL5504843 | 0.83 | SIGMAR1 (0.44) | KDM4ESIGMAR1CHRM2CHRM1HRH3 | |
| SCHEMBL5502187 | 0.83 | HRH3 (0.44) | LMNARAB9ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL5507629 | 0.81 | LMNA (0.41) | KDM4ELMNARAB9AKEAP1SMN1; SMN2 | |
| SCHEMBL5504842 | 0.77 | HRH3 (0.35) | SMN1; SMN2ALDH1A1SIGMAR1HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |