Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157251 | 0.85 | TSHR (0.71) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL28599511 | 0.82 | HTR3E (0.73) | LMNATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29656856 | 0.82 | HTR3E (0.73) | LMNATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12463334 | 0.80 | LMNA (0.64) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL2155086 | 0.78 | LMNA (0.58) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL4959574 | 0.77 | LMNA (0.57) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL13090000 | 0.77 | L3MBTL1 (0.62) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL4959570 | 0.76 | LMNA (0.59) | LMNATSHRSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL9483779 | 0.76 | HSD17B10 (0.66) | ALDH1A1MEN1KMT2ADRD2 | |
| SCHEMBL2156468 | 0.76 | LMNA (0.52) | LMNATSHRSMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | disclosed |