Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.30 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502598 | 0.88 | AHR (0.30) | AHRTDP2HDAC3 | |
| SCHEMBL5498389 | 0.85 | DRD2 (0.33) | AHRTDP2HDAC3GRIA1CACNG8 | |
| SCHEMBL5507259 | 0.81 | GRIN1 (0.31) | — | |
| SCHEMBL5504614 | 0.80 | HDAC3 (0.35) | AHRTDP2HDAC3GRIA1CACNG8 | |
| SCHEMBL5502610 | 0.77 | TDP2 (0.36) | TDP2GRIA1 | |
| SCHEMBL5502292 | 0.76 | AHR (0.32) | AHRTDP2HDAC3GRIA1CACNG8 | |
| SCHEMBL5505582 | 0.73 | EPHX2 (0.33) | AHRTDP2HDAC3GRIA1CACNG8 | |
| SCHEMBL151642 | 0.70 | HDAC3 (0.40) | AHRTDP2HDAC3GRIA1CACNG8 | |
| SCHEMBL5505297 | 0.70 | GRIA1 (0.39) | AHRTDP2GRIA1CACNG8 | |
| SCHEMBL5499274 | 0.70 | TDP2 (0.35) | TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869030-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006106427-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |