Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501533 | 0.78 | HRH3 (0.33) | LMNA | |
| SCHEMBL21871331 | 0.76 | ALDH1A1 (0.44) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL10092701 | 0.76 | ALDH1A1 (0.44) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL5502126 | 0.76 | SIGMAR1 (0.38) | SIGMAR1EBPLMNAMEN1MAPT | |
| SCHEMBL5504819 | 0.75 | NSD2 (0.36) | LMNAMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL25122519 | 0.73 | LMNA (0.39) | SIGMAR1LMNAMEN1MAPTKMT2A | |
| SCHEMBL5505363 | 0.72 | HRH3 (0.36) | — | |
| SCHEMBL5505366 | 0.72 | HRH3 (0.36) | — | |
| SCHEMBL4386733 | 0.72 | HRH3 (0.42) | SIGMAR1EBPLMNAMEN1MAPT | |
| SCHEMBL4386729 | 0.72 | HRH3 (0.42) | SIGMAR1EBPLMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |