Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FSHR | P23945 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568293 | 0.79 | TAAR1 (0.53) | TAAR1AOC3HTTCYP51A1EGFR | |
| SCHEMBL8909554 | 0.77 | ALDH1A1 (0.52) | TSHRTDP1L3MBTL1LMNAMAPK1 | |
| SCHEMBL5112506 | 0.74 | TDP1 (0.48) | TSHRTDP1L3MBTL1LMNACYP3A4 | |
| SCHEMBL2420022 | 0.74 | TSHR (0.50) | TSHRTDP1L3MBTL1HTTLMNA | |
| SCHEMBL14759196 | 0.72 | NAAA (0.50) | TSHRLMNATP53CYP3A4MAPK1 | |
| SCHEMBL25226358 | 0.70 | NAAA (0.53) | TSHRLMNAALDH1A1 | |
| SCHEMBL14759435 | 0.70 | NAAA (0.53) | TSHRLMNAALDH1A1 | |
| SCHEMBL25229297 | 0.70 | NAAA (0.53) | TSHRLMNAALDH1A1 | |
| SCHEMBL65775 | 0.70 | ALDH1A1 (0.52) | TSHRTDP1L3MBTL1LMNACYP3A4 | |
| SCHEMBL28960395 | 0.70 | TAAR1 (0.51) | TAAR1AOC3TDP1CYP51A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | disclosed |