Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132648 | 0.83 | ALDH1A1 (0.37) | MGAMGAASIMGAM2 | |
| SCHEMBL3228082 | 0.78 | THRB (0.32) | — | |
| SCHEMBL12272261 | 0.78 | SOAT1 (0.32) | — | |
| SCHEMBL5047600 | 0.78 | LMNA (0.33) | — | |
| SCHEMBL12271661 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL12272631 | 0.73 | — | — | |
| SCHEMBL1495932 | 0.72 | CA1 (0.31) | — | |
| SCHEMBL5045856 | 0.72 | ACACB (0.31) | — | |
| SCHEMBL5049024 | 0.71 | ACACB (0.30) | — | |
| SCHEMBL2955397 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466830-A | Preparation from a phenol and 4-dialkoxy-2-butynoic acid ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-14 | — | — | US | claimed |
| US-20160114057-A1 | MODULAR PROTEIN DRUG CONJUGATE THERAPEUTIC | ZYEWORKS INC. (CA) | 2016-04-28 | — | — | US | disclosed |
| CN-101237892-A | Method for conjugating molecules containing an aminothiol to a carrier | AMGEN INC (US) | 2008-08-06 | — | — | CN | disclosed |
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | AMGEN INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| EP-0918757-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997043268-A1 | 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS | GEORGETOWN UNIVERSITY (US) | 1997-11-20 | — | — | WO | disclosed |
| US-5466830-A | Preparation from a phenol and 4-dialkoxy-2-butynoic acid ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |
| US-5336687-A | For treating osteoporosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114057-A1 | MODULAR PROTEIN DRUG CONJUGATE THERAPEUTIC | FCGRT, BCR, ERBB3 | MGAM 859/4885GAA 579/4885SI 3509/4885 |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | SLC7A1, QPCT, SLC7A5 | MGAM 2863/4885GAA 2174/4885SI 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.