SCHEMBL5503280

SCHEMBL5503280

CNC(CCCCN)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.44
FOLH1 Q04609 2/20 0.41
CPB2 Q96IY4 2/20 0.41
GSR P00390 1/20 0.39
ERAP2 Q6P179 4/20 0.39
LNPEP Q9UIQ6 4/20 0.39
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
ERAP1 Q9NZ08 1/20 0.39
CNR2 P34972 1/20 0.39
RNPEP Q9H4A4 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4912676 1.00 ANPEP (0.44) ANPEPFOLH1CPB2GSRERAP2
Hydrochloric Acid SCHEMBL7202066 0.98 ANPEP (0.43) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL27593963 0.94 ANPEP (0.39) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL12890801 0.94 ANPEP (0.39) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL16263606 0.88 ERAP2 (0.43) ANPEPFOLH1ERAP2LNPEPSIRT6
SCHEMBL18720312 0.85 CPB2 (0.39) ANPEPFOLH1CPB2GSRSIRT6
SCHEMBL7224727 0.85 ANPEP (0.44) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL7224725 0.85 ANPEP (0.44) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL7576584 0.85 ANPEP (0.44) ANPEPFOLH1CPB2GSRERAP2
SCHEMBL12013082 0.83 ANPEP (0.46) ANPEPFOLH1CPB2GSRERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786642-B2 In situ forming hemostatic form implants ARSENAL MEDICAL, INC. (US) 2023-10-17 US disclosed
US-11786642-B2 In situ forming hemostatic form implants ARSENAL MEDICAL, INC. (US) 2023-10-17 US disclosed
US-20230263900-A1 DENDRIMER-DRUG CONJUGATE STARPHARMA PTY LTD (AU) 2023-08-24 US disclosed
US-20230241360-A1 TEMPORARY OCCLUSION BALLOON DEVICES AND METHODS FOR PREVENTING BLOOD FLOW THROUGH A VASCULAR PERFORATION SPECTRANETICS LLC (CO) 2023-08-03 US disclosed
US-20230241360-A1 TEMPORARY OCCLUSION BALLOON DEVICES AND METHODS FOR PREVENTING BLOOD FLOW THROUGH A VASCULAR PERFORATION SPECTRANETICS LLC (CO) 2023-08-03 US disclosed
US-20220105248-A1 IN SITU FORMING HEMOSTATIC FOAM IMPLANTS ARSENAL MEDICAL, INC. 2022-04-07 US disclosed
US-11246964-B2 In situ forming hemostatic foam implants ARSENAL MEDICAL, INC. (US) 2022-02-15 US disclosed
US-10980920-B2 In situ forming hemostatic foam implants ARSENAL MEDICAL, INC. (US) 2021-04-20 US disclosed
US-20200405921-A1 IN SITU FORMING HEMOSTATIC FORM IMPLANTS ARSENAL MEDICAL, INC. 2020-12-31 US disclosed
EP-2673293-B1 SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF HARVARD COLLEGE (US) 2020-09-16 EP disclosed
US-20120265287-A1 In-Situ Forming Foams for Treatment of Aneurysms ARSENAL MEDICAL, INC. (US) 2012-10-18 US disclosed
US-20120265287-A1 In-Situ Forming Foams for Treatment of Aneurysms ARSENAL MEDICAL, INC. (US) 2012-10-18 US disclosed
US-20120107439-A1 IN SITU FORMING HEMOSTATIC FOAM IMPLANTS ARSENAL MEDICAL, INC. (US) 2012-05-03 US disclosed
US-20120107439-A1 IN SITU FORMING HEMOSTATIC FOAM IMPLANTS ARSENAL MEDICAL, INC. (US) 2012-05-03 US disclosed
US-20110294995-A1 Functionalized nanoparticles and other particles and methods for making and using same NORTH DAKOTA STATE UNIVERSITY 2011-12-01 US disclosed
US-20110202016-A1 SYSTEMS AND METHODS RELATING TO POLYMER FOAMS ARSENAL MEDICAL, INC. (US) 2011-08-18 US disclosed
US-20110202016-A1 SYSTEMS AND METHODS RELATING TO POLYMER FOAMS ARSENAL MEDICAL, INC. (US) 2011-08-18 US disclosed
US-20100226967-A1 IMAGING AND THERAPEUTIC METHOD USING PROGENITOR CELLS PURDUE RESEARCH FOUNDATION (US) 2010-09-09 US disclosed
US-20100055735-A1 EX VIVO FLOW CYTOMETRY METHOD AND DEVICE LOW PHILIP STEWART 2010-03-04 US disclosed
US-20070134335-A1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA S.A. (ES) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070134335-A1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY DNPEP, LNPEP, PTMS ANPEP 7/4885FOLH1 51/4885CPB2 497/4885
US-20100226967-A1 IMAGING AND THERAPEUTIC METHOD USING PROGENITOR CELLS CD44, MYADM, ANTXR2 ANPEP 947/4885FOLH1 316/4885CPB2 591/4885
US-20110294995-A1 Functionalized nanoparticles and other particles and methods for making and using same NCL, RNGTT, CD63 ANPEP 387/4885FOLH1 487/4885CPB2 3225/4885
US-20230263900-A1 DENDRIMER-DRUG CONJUGATE SARS1, MMAB, PAM ANPEP 105/4885FOLH1 27/4885CPB2 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.