Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499002 | 0.79 | TDP2 (0.38) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5504412 | 0.78 | TDP2 (0.34) | TDP2PGRCYP11B1CYP11B2BCL6 | |
| SCHEMBL5505582 | 0.77 | EPHX2 (0.33) | TDP2EPHX2 | |
| SCHEMBL5502610 | 0.76 | TDP2 (0.36) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5504827 | 0.76 | TDP2 (0.36) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5498328 | 0.75 | TDP2 (0.35) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL3139883 | 0.74 | TDP2 (0.41) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5499274 | 0.74 | TDP2 (0.35) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5498091 | 0.70 | PGR (0.43) | TDP2PGRBCL6BCOREPHX2 | |
| SCHEMBL30062441 | 0.70 | CYP11B1 (0.48) | PGRCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869030-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006106427-A1 | 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |