Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502610 | 0.83 | TDP2 (0.36) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5498328 | 0.82 | TDP2 (0.35) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5499274 | 0.81 | TDP2 (0.35) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5507259 | 0.79 | GRIN1 (0.31) | — | |
| SCHEMBL5503483 | 0.78 | TDP2 (0.36) | TDP2PGRCYP11B1CYP11B2BCL6 | |
| SCHEMBL5499002 | 0.76 | TDP2 (0.38) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5504827 | 0.73 | TDP2 (0.36) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5501521 | 0.73 | PGR (0.40) | TDP2PGRBCL6BCOR | |
| SCHEMBL3139883 | 0.71 | TDP2 (0.41) | TDP2PGRCYP11B1CYP11B2 | |
| SCHEMBL5502203 | 0.68 | F10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |