Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744136 | 0.75 | TLR7 (0.62) | HDAC1HDAC6 | |
| SCHEMBL4586839 | 0.64 | TLR7 (0.38) | — | |
| SCHEMBL5276268 | 0.61 | TLR8 (0.42) | — | |
| SCHEMBL3977482 | 0.61 | TLR7 (0.37) | — | |
| SCHEMBL24596987 | 0.61 | CTSB (0.59) | CA2CA5ACTSBCTSKMEN1 | |
| SCHEMBL14595222 | 0.61 | CTSB (0.59) | CA2CA5ACTSBCTSKMEN1 | |
| SCHEMBL6897148 | 0.61 | CTSB (0.57) | CTSBCTSKMEN1KMT2A | |
| SCHEMBL23051873 | 0.61 | CTSB (0.59) | CTSBCTSKMEN1KMT2A | |
| SCHEMBL1908598 | 0.61 | CTSK (0.62) | CA2CA5ACTSBCTSKMEN1 | |
| SCHEMBL28892051 | 0.61 | TRPM8 (0.62) | CA2CA5ACTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850849-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | Coley Pharmaceutical Group, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006091647-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |