Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505166 | 0.77 | ADORA3 (0.62) | ADORA3ADORA2AADORA1 | |
| SCHEMBL31060487 | 0.74 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29602474 | 0.73 | ADORA2A (0.51) | ADORA3ADORA2AADORA1CNR1 | |
| SCHEMBL2974505 | 0.73 | ADORA3 (0.49) | ADORA3ADORA2AADORA1CNR1 | |
| SCHEMBL31061120 | 0.71 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL5505165 | 0.70 | ADORA3 (0.47) | ADORA3ADORA2AADORA1CNR1 | |
| SCHEMBL85621 | 0.68 | GPR3 (1.00) | ADORA3 | |
| SCHEMBL5503114 | 0.68 | ADORA3 (1.00) | ADORA3ADORA2AADORA1CNR1 | |
| SCHEMBL17335816 | 0.68 | KDM4E (0.60) | ADORA3ADORA1CNR1 | |
| SCHEMBL2979520 | 0.67 | ESR2 (0.62) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863813-A2 | PYRAZOLO[3,4-C]QUINOLINES, PYRAZOLO[3,4-C]NAPHTHYRIDINES, ANALOGS THEREOF, AND METHODS | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107771-A2 | PYRAZOLO[3,4-c]QUINOLINES, PYRAZOLO[3,4-c]NAPHTHYRIDINES, ANALOGS THEREOF, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |