Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504183 | 0.77 | ADORA3 (0.68) | ADORA3ADORA2AADORA1 | |
| SCHEMBL5507108 | 0.76 | TLR7 (0.57) | ADORA3ADORA2AADORA1KMT2A | |
| SCHEMBL18470455 | 0.71 | KMT2A (1.00) | ADORA3KMT2A | |
| SCHEMBL31061120 | 0.68 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL31060487 | 0.68 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL5507703 | 0.67 | ADORA3 (0.71) | ADORA3ADORA2AADORA1 | |
| SCHEMBL29602139 | 0.66 | ADORA3 (0.49) | ADORA3ADORA2AADORA1 | |
| SCHEMBL2979520 | 0.64 | ESR2 (0.62) | ADORA3ADORA2AADORA1KMT2A | |
| SCHEMBL5505165 | 0.64 | ADORA3 (0.47) | ADORA3ADORA2AADORA1 | |
| SCHEMBL5508801 | 0.63 | ADORA3 (0.83) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863813-A2 | PYRAZOLO[3,4-C]QUINOLINES, PYRAZOLO[3,4-C]NAPHTHYRIDINES, ANALOGS THEREOF, AND METHODS | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107771-A2 | PYRAZOLO[3,4-c]QUINOLINES, PYRAZOLO[3,4-c]NAPHTHYRIDINES, ANALOGS THEREOF, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |