Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156328 | 0.88 | HNF4A (0.53) | BCAT2ALDH1A1L3MBTL1CYP3A4KDM4E | |
| SCHEMBL30013864 | 0.87 | SLC6A3 (0.48) | BCAT2ALDH1A1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL1667777 | 0.84 | BCAT2 (0.56) | BCAT2KDM4EPARP1 | |
| SCHEMBL30504310 | 0.83 | BCAT2 (0.62) | BCAT2ALDH1A1L3MBTL1KDM4EHNF4A | |
| SCHEMBL3975515 | 0.82 | BCAT2 (0.54) | BCAT2L3MBTL1CYP3A4KDM4ETDP1 | |
| SCHEMBL3973836 | 0.82 | BCAT2 (0.54) | BCAT2ALDH1A1L3MBTL1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL30628503 | 0.81 | BCAT2 (0.61) | BCAT2ALDH1A1L3MBTL1KDM4EHNF4A | |
| Hydrochloric Acid SCHEMBL30504328 | 0.81 | BCAT2 (0.61) | BCAT2ALDH1A1L3MBTL1KDM4EHNF4A | |
| SCHEMBL13828076 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2 | |
| SCHEMBL22468856 | 0.79 | PARP10 (0.53) | BCAT2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |