Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749505 | 0.88 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL875475 | 0.85 | PARP1 (0.60) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL27966084 | 0.84 | PARP1 (0.58) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL2362774 | 0.83 | FABP3 (0.58) | LMNAGLARAB9AHTTPARP1 | |
| Ethenzamide SCHEMBL27612766 | 0.82 | MAPT (0.68) | CYP3A4L3MBTL1MEN1KMT2ALMNA | |
| Ethenzamide SCHEMBL25624 | 0.82 | MAPT (0.68) | CYP3A4L3MBTL1MEN1KMT2ALMNA | |
| Ethenzamide SCHEMBL4379591 | 0.80 | MAPT (0.66) | CYP3A4L3MBTL1MEN1KMT2ALMNA | |
| Ethenzamide SCHEMBL22163775 | 0.80 | MAPT (0.66) | CYP3A4L3MBTL1MEN1KMT2ALMNA | |
| Ethenzamide SCHEMBL5401172 | 0.80 | MAPT (0.66) | CYP3A4L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL28192819 | 0.78 | LMNA (0.48) | CYP3A4CYP1A2CYP2C19L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |