Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361670 | 0.87 | FABP3 (0.51) | FABP3FABP4FABP5HTTCTNNB1 | |
| SCHEMBL5845535 | 0.86 | FABP4 (0.70) | FABP3FABP4FABP5HTTNPC1 | |
| SCHEMBL2567371 | 0.86 | TP53 (0.45) | FABP3FABP4FABP5HTTNPC1 | |
| SCHEMBL7174236 | 0.83 | FABP4 (0.62) | FABP3FABP4FABP5HTTNPC1 | |
| SCHEMBL7430974 | 0.83 | FABP4 (0.58) | FABP3FABP4FABP5HTTNPC1 | |
| SCHEMBL22468857 | 0.83 | IRAK4 (0.46) | FABP3FABP4FABP5HTTCTNNB1 | |
| SCHEMBL5504646 | 0.83 | CYP3A4 (0.49) | HTTCTNNB1BCAT2IRAK4RAB9A | |
| SCHEMBL30343294 | 0.82 | MKNK1 (0.64) | PARP1POLB | |
| SCHEMBL27214460 | 0.82 | BCAT2 (0.63) | FABP4CTNNB1BCAT2KEAP1NFE2L2 | |
| SCHEMBL8799869 | 0.81 | FABP3 (0.56) | FABP3FABP4FABP5HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863832-A | A kind of preparation method of N- arylamides | 河南大学 | 2018-11-23 | — | — | CN | disclosed |
| EP-2536286-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | Siga Technologies, Inc. (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103375-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | SIGA TECHNOLOGIES, INC. (US) | 2011-08-25 | — | — | WO | disclosed |