SCHEMBL5505142

SCHEMBL5505142

[C]1=Cc2ccccc2C1Cc1ccccn1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
HRH1 P35367 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36
LIN28A Q9H9Z2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HSD17B10 Q99714 1/20 0.33
SYK P43405 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754873 0.69 HTR6 (0.51) LMNAHRH1SMN1; SMN2MAPTLIN28A
Hydrochloric Acid SCHEMBL1072138 0.68 LMNA (0.37) LMNAHRH1SMN1; SMN2MAPTLIN28A
SCHEMBL9731494 0.67 HTR2A (0.45) LMNAHRH1SMN1; SMN2MAPTLIN28A
SCHEMBL6760470 0.67 LMNA (0.36) LMNAHRH1SMN1; SMN2MAPTLIN28A
SCHEMBL1515445 0.64 SMN1; SMN2 (0.48) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL8911524 0.63 HPGD (0.55) HRH1SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL7790597 0.63
SCHEMBL27560598 0.62 HRH1 (0.45) LMNAHRH1SMN1; SMN2MAPTLIN28A
Bromide SCHEMBL28182316 0.62 HPGD (0.54) HRH1SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL465245 0.61 HRH1 (0.44) LMNAHRH1SMN1; SMN2MAPTLIN28A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861409-A1 MONOCYCLOPENTADIENYL COMPLEXES Basell Polyolefine GmbH (DE) 2007-12-05 EP disclosed
EP-1740626-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE Basell Polyolefine GmbH (DE) 2007-01-10 EP disclosed
WO-2006100004-A1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2006-09-28 WO disclosed
WO-2005103099-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE BASELL POLYOLEFINE GMBH (DE) 2005-11-03 WO disclosed