Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086937 | 1.00 | MAPT (0.47) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL27567577 | 0.84 | TP53 (0.51) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL727643 | 0.84 | MAPT (0.40) | MAPTKMT2ARAB9AMAPK1GAA | |
| Benzoic Acid SCHEMBL28982992 | 0.76 | PKM (0.43) | MAPTKMT2ARAB9AMAPK1MEN1 | |
| SCHEMBL30872986 | 0.74 | RIPK1 (0.53) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL8484519 | 0.74 | CYP19A1 (0.47) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL2879152 | 0.74 | CA1 (0.42) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL3197529 | 0.73 | CYP19A1 (0.46) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL31217569 | 0.72 | HPGD (0.50) | MAPTKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL28921922 | 0.71 | CA1 (0.44) | MAPTKMT2ANPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641183-B | Prevention and treatment of vascular calcification and cardiovascular/related diseases | 顶峰创新实验室有限公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-1833456-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | The Procter and Gamble Company (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1778177-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | The Procter and Gamble Company (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1771149-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | The Procter and Gamble Company (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006020163-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | THE PROCTER & GAMBLE COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2006020164-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | THE PROCTER & GAMBLE COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2006020165-A1 | SKIN CARE COMPOSITION CONTAINING A FLAVONOID AND VITAMIN B3 | THE PROCTER & GAMBLE COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |