SCHEMBL727643

SCHEMBL727643

O=C1c2ccccc2OC(O)(c2ccccc2)C1(O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 5/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
CA7 P43166 1/20 0.39
RECQL P46063 1/20 0.39
BACE1 P56817 1/20 0.39
CA9 Q16790 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL28982992 0.91 PKM (0.43) MAPTGAACFTRGOPCRAB9A
SCHEMBL5505263 0.84 MAPT (0.47) MAPTGAARAB9ASMN1; SMN2ALDH1A1
SCHEMBL31086937 0.84 MAPT (0.47) MAPTGAARAB9ASMN1; SMN2ALDH1A1
SCHEMBL7049756 0.79 ALDH1A1 (0.42) MAPTGAACFTRGOPCSMN1; SMN2
SCHEMBL27567577 0.78 TP53 (0.51) MAPTGAARAB9ASMN1; SMN2ALDH1A1
SCHEMBL29170016 0.78 ALDH1A1 (0.31) MAPTALDH1A1ALOX12RECQLL3MBTL1
SCHEMBL30689853 0.78 CA1 (0.39) MAPTRAB9ASMN1; SMN2ALDH1A1CA1
SCHEMBL3698500 0.78 CA1 (0.39) MAPTRAB9ASMN1; SMN2ALDH1A1CA1
SCHEMBL2679213 0.75 ALDH1A1 (0.39) MAPTSMN1; SMN2ALDH1A1CA1CA2
SCHEMBL4226505 0.75 ALDH1A1 (0.43) MAPTGAACFTRGOPCRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119320777-A Metabolite screening method for promoting expression of porcine intestinal defensin pBD1 and application thereof 浙江大学 2025-01-17 CN claimed
US-20240301326-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt Benckiser Health Limited (GB) 2024-09-12 US claimed
EP-4373906-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-05-29 EP claimed
CN-117716012-A Cage-free self-adhesive toilet cleaning composition 雷克特和科尔曼(海外)家用卫生有限公司 2024-03-15 CN claimed
US-20230248755-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH BioRelief, LLC (US) 2023-08-10 US claimed
CN-115787325-A Polyester low-temperature dyeing accelerant and preparation method thereof 太仓宝霓实业有限公司 2023-03-14 CN claimed
WO-2023002214-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2023-01-26 WO claimed
US-20210060048-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH BIORELIEF LLC (US) 2021-03-04 US claimed
CN-108850148-A 7,2 ', 4 '-trihydroxy flavanone carboxymethyl cellulose composite membranes and its application 泉州师范学院 2018-11-23 CN claimed
CN-105866445-A Liquid-phase thrombin time determining reagent and preparation method thereof 青岛古高生物科技有限公司 2016-08-17 CN claimed
EP-1429602-A4 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS UNIV RUTGERS (US) 2005-12-21 EP claimed
US-20050069598-A1 Methods for treating disorders using plant extracts RIBNICKY DAVID M (US) 2005-03-31 US claimed
JP-2005505544-A 2005-02-24 JP claimed
US-20040180800-A1 Cleaning and protecting composition with antioxidant and UV light resistance and method of use HOMECARE LABS, INC. 2004-09-16 US claimed
EP-1429602-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2004-06-23 EP claimed
US-20030072822-A1 Methods for treating disorders using plant extracts RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY 2003-04-17 US claimed
WO-2003020026-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2003-03-13 WO claimed
EP-1067913-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS Bioresponse, L.L.C. (US) 2001-01-17 EP claimed
WO-1999049851-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS BIORESPONSE, L.L.C. (US) 1999-10-07 WO claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210060048-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH TRPV1, CALCB, TRPV2 MAPT 4869/4885GAA 4771/4885CFTR 410/4885
US-20230248755-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH TRPV1, CALCB, TRPV2 MAPT 4869/4885GAA 4771/4885CFTR 410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.