Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679213 | 0.83 | ALDH1A1 (0.39) | CA1CA2CA7CA9PDK2 | |
| SCHEMBL7049756 | 0.78 | ALDH1A1 (0.42) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5505263 | 0.74 | MAPT (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL31086937 | 0.74 | MAPT (0.47) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL727643 | 0.70 | MAPT (0.40) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL28921922 | 0.70 | CA1 (0.44) | CA1CA2CA7CA9PDK2 | |
| Flavanone SCHEMBL3438655 | 0.70 | MAOB (0.55) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL4824717 | 0.69 | TP53 (0.52) | CA1CA2CA7CA9PDK2 | |
| SCHEMBL1118992 | 0.66 | CA1 (0.38) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL6239972 | 0.66 | CYP19A1 (0.42) | CA1CA2CA7CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784201-B1 | PHYSIOLOGICALLY ACTIVE COMPOSITION AGAINST DIABETES | PHYTOMEDICS INC (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20090142425-A1 | Physiologically active composition | PHYTOMEDICS INCORPORATED | 2009-06-04 | — | — | US | disclosed |
| EP-1784201-A2 | PHYSIOLOGICALLY ACTIVE COMPOSITION | Cargill, Incorporated (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006010560-A2 | PHYSIOLOGICALLY ACTIVE COMPOSITION | CARGILL, INCORPORATED (US) | 2006-02-02 | — | — | WO | disclosed |