Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509224 | 0.85 | ADRB1 (0.39) | ADRB1HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL5506120 | 0.83 | ADRB1 (0.49) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5509277 | 0.83 | ADRB1 (0.46) | ADRB1HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL5505025 | 0.80 | MAOA (0.41) | ADRB1MAPTHTR2CHTR2AHTR2B | |
| SCHEMBL5504235 | 0.77 | HTR2C (0.41) | HTR2CHTR2AHTR2BKMT2ASLC6A2 | |
| SCHEMBL653307 | 0.76 | HTR3A (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL335933 | 0.76 | HTR3A (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL653028 | 0.76 | HTR3A (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5511689 | 0.76 | CMA1 (0.41) | MAPTHTR2CHTR2AHTR2BKMT2A | |
| Hydrochloric Acid SCHEMBL5632640 | 0.75 | HTR3A (0.49) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | disclosed |