Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.41 |
| ▸ | HTR2B | P41595 | 9/20 | 0.41 |
| ▸ | HTR2A | P28223 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506120 | 0.83 | ADRB1 (0.49) | HTR2CHTR2BHTR2AKMT2ALMNA | |
| SCHEMBL5509224 | 0.77 | ADRB1 (0.39) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL5506261 | 0.77 | ADRB1 (0.44) | HTR2CHTR2BHTR2AKMT2ASLC6A2 | |
| SCHEMBL5511689 | 0.76 | CMA1 (0.41) | HTR2CHTR2BHTR2AKMT2APKM | |
| SCHEMBL5509277 | 0.75 | ADRB1 (0.46) | HTR2CHTR2BHTR2AKMT2ASLC6A2 | |
| SCHEMBL5505025 | 0.74 | MAOA (0.41) | HTR2CHTR2BHTR2AKMT2ALMNA | |
| SCHEMBL4981272 | 0.70 | PDE4B (0.57) | KMT2ALMNA | |
| SCHEMBL361649 | 0.70 | ADRB1 (0.61) | LMNA | |
| SCHEMBL21098717 | 0.68 | KDR (0.46) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL21098716 | 0.68 | KDR (0.46) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | disclosed |