Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507418 | 0.78 | HPGD (0.43) | HPGDRECQLEPHX1KDM4EPKM | |
| SCHEMBL24745481 | 0.74 | HPGD (0.46) | HPGDRECQLEPHX1KDM4EALDH1A1 | |
| SCHEMBL1795814 | 0.74 | HPGD (0.46) | HPGDRECQLEPHX1ALDH1A1MAPT | |
| SCHEMBL16292818 | 0.74 | HPGD (0.44) | HPGDEPHX1KDM4EPKMGPR119 | |
| SCHEMBL8912276 | 0.74 | GPR119 (0.40) | HPGDRECQLEPHX1KDM4EPKM | |
| SCHEMBL1479749 | 0.74 | ACHE (0.48) | HPGDRECQLEPHX1ALDH1A1GPR119 | |
| SCHEMBL5506815 | 0.74 | RECQL (0.40) | HPGDRECQLEPHX1GPR119 | |
| SCHEMBL4387707 | 0.74 | TP53 (0.43) | HPGDRECQLEPHX1KDM4EPKM | |
| SCHEMBL2958093 | 0.73 | HPGD (0.48) | HPGDRECQLEPHX1KDM4EPKM | |
| SCHEMBL23384349 | 0.73 | HPGD (0.45) | HPGDRECQLEPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |