Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7128367 | 0.85 | PDCD1 (0.32) | PDCD1CD274ALDH1A1HSD17B10CHRNB2 | |
| Hydrochloric Acid SCHEMBL5513584 | 0.83 | METAP2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5518571 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6138837 | 0.80 | BRD4 (0.31) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL27537901 | 0.78 | PDCD1 (0.35) | PDCD1CD274ALDH1A1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL5513889 | 0.78 | ESR2 (0.32) | — | |
| SCHEMBL7525652 | 0.76 | PDCD1 (0.36) | PDCD1CD274ALDH1A1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL5709184 | 0.75 | PDCD1 (0.35) | PDCD1CD274ALDH1A1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL3163965 | 0.75 | PDCD1 (0.35) | PDCD1CD274ALDH1A1HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL29424591 | 0.75 | PDCD1 (0.35) | PDCD1CD274ALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725537-B2 | High activity catalyst supportation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-08 | — | — | US | claimed |
| WO-2019199824-A1 | HETEROPHASIC COPOLYMERS AND POLYMERIZATION METHODS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-10-17 | — | — | WO | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| US-5993964-A | PROPYLENE-ETHYLENE COPOLYMER HAVING CHARACTERISTIC ETHYLENE CHAINS, AN EXTREMELY LOW AMOUNT OF REVERSE INSERTION OF PROPYLENE MONOMER UNITS, AND A NARROW MOLECULAR WEIGHT DISTRIBUTION. | CHISSO CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0875609-A2 | Fibers and fibrous moldings using the same | CHISSO CORPORATION (JP) | 1998-11-04 | — | — | EP | disclosed |