Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507425 | 0.78 | HPGD (0.43) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL16292818 | 0.77 | HPGD (0.44) | HPGDGPR119EPHX1KDM4EPKM | |
| SCHEMBL4387707 | 0.72 | TP53 (0.43) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL5507423 | 0.71 | HPGD (0.41) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL1085043 | 0.70 | HPGD (0.49) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL1085044 | 0.70 | HPGD (0.49) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL1720172 | 0.70 | HPGD (0.49) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL5500642 | 0.69 | DRD2 (0.43) | RECQL | |
| SCHEMBL20292138 | 0.69 | HPGD (0.48) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL2958093 | 0.69 | HPGD (0.48) | HPGDRECQLEPHX1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |