Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387709 | 0.75 | GPR119 (0.39) | HPGDGPR119MAPT | |
| SCHEMBL16292818 | 0.72 | HPGD (0.44) | HPGDGPR119EPHX1KDM4EPKM | |
| SCHEMBL5507425 | 0.71 | HPGD (0.43) | HPGDRECQLGPR119EPHX1KDM4E | |
| SCHEMBL5507418 | 0.71 | HPGD (0.43) | HPGDRECQLGPR119EPHX1KDM4E | |
| SCHEMBL310117 | 0.68 | GPR119 (0.67) | HPGDRECQLGPR119EPHX1USP2 | |
| SCHEMBL3784890 | 0.67 | GPR119 (0.55) | HPGDRECQLGPR119EPHX1USP2 | |
| SCHEMBL2881367 | 0.67 | GPR119 (0.55) | HPGDRECQLGPR119EPHX1USP2 | |
| SCHEMBL2881371 | 0.67 | GPR119 (0.55) | HPGDRECQLGPR119EPHX1USP2 | |
| SCHEMBL21359212 | 0.67 | EPHX1 (0.62) | HPGDRECQLGPR119EPHX1USP2 | |
| SCHEMBL2958093 | 0.66 | HPGD (0.48) | HPGDRECQLEPHX1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |