Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387707 | 0.75 | TP53 (0.43) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5507423 | 0.75 | HPGD (0.41) | GPR119MAPTHPGD | |
| SCHEMBL16292818 | 0.67 | HPGD (0.44) | GPR119HPGD | |
| SCHEMBL4386758 | 0.66 | GPR119 (0.43) | GPR119MAPTHPGD | |
| SCHEMBL5507418 | 0.66 | HPGD (0.43) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5507425 | 0.66 | HPGD (0.43) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8874070 | 0.65 | GPR119 (0.47) | GPR119MAPT | |
| SCHEMBL4393986 | 0.63 | HRH3 (0.57) | — | |
| SCHEMBL31735223 | 0.63 | NR1H2 (0.50) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL310117 | 0.63 | GPR119 (0.67) | GPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | GPR119 1988/4885MEN1 3396/4885ALDH1A1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.