Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551735 | 0.84 | TSHR (0.42) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL3778792 | 0.77 | MAPK1 (0.55) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL30822033 | 0.77 | MAPK1 (0.55) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL19179770 | 0.76 | APP (0.48) | TSHRALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL24191114 | 0.74 | GPR35 (0.56) | ALDH1A1TDP1HPGDALOX15HIF1A | |
| SCHEMBL30429503 | 0.74 | GPR35 (0.56) | ALDH1A1TDP1HPGDALOX15HIF1A | |
| SCHEMBL1755269 | 0.73 | MAPT (0.51) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL550419 | 0.72 | TSHR (0.44) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL550823 | 0.72 | TSHR (0.44) | TSHRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL550878 | 0.71 | TSHR (0.57) | TSHRALDH1A1TDP1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110689-B2 | Benzanilides with insecticidal activity | BAYER CROPSCIENE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8110689-B2 | Benzanilides with insecticidal activity | BAYER CROPSCIENE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | US | disclosed |
| EP-1893567-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | Bayer CropScience AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133823-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | CBR3, HCN3, HAX1 | TSHR 926/4885ALDH1A1 2102/4885TDP1 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.