Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510283 | 0.85 | KMT2A (0.57) | LMNAKMT2AMEN1TSHRCYP2C19 | |
| SCHEMBL2112323 | 0.83 | LMNA (0.68) | LMNAKMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL5205623 | 0.82 | LMNA (0.65) | LMNAKMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL5508063 | 0.81 | KMT2A (0.55) | LMNAKMT2AMEN1TSHRCYP2C19 | |
| SCHEMBL10002472 | 0.79 | LMNA (0.60) | LMNAKMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL28740690 | 0.77 | HRH3 (0.55) | LMNAKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL18892800 | 0.77 | PSMB1 (0.54) | LMNAKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL4992446 | 0.75 | LMNA (0.59) | LMNAKMT2AMEN1TSHRCYP3A4 | |
| SCHEMBL1480336 | 0.75 | LMNA (0.55) | LMNAKMT2ACYP3A4CYP2C19KDM4E | |
| SCHEMBL7141114 | 0.74 | LMNA (0.55) | LMNAKMT2AMEN1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |