SCHEMBL5508448

SCHEMBL5508448

Nc1c(F)c(F)cc2c(O)c(F)c(F)cc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5514095 0.85 CES2 (0.38) CES2CES1
SCHEMBL5515482 0.85 CA12 (0.35) CES2CES1
SCHEMBL5508766 0.81 HSD17B1 (0.33)
SCHEMBL5516180 0.77 HSD17B1 (0.33) CES2CES1
SCHEMBL5506992 0.73 CA1 (0.36) CES2CES1
SCHEMBL5514314 0.73 CA3 (0.34) CES2CES1
SCHEMBL5507490 0.73 ALDH1A1 (0.30)
SCHEMBL5517778 0.71 CA9 (0.38) CES2CES1
SCHEMBL5507531 0.71 ALDH1A1 (0.33) CES2CES1
SCHEMBL5515941 0.71 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed