Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603962 | 0.84 | TP53 (0.61) | KMT2AALOX5L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL25336401 | 0.80 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5512049 | 0.80 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13603966 | 0.79 | ALDH1A1 (0.46) | KMT2AL3MBTL1MEN1ALDH1A1HTT | |
| SCHEMBL5932403 | 0.79 | ALDH1A1 (0.46) | KMT2AL3MBTL1MEN1ALDH1A1HTT | |
| SCHEMBL13479771 | 0.79 | TP53 (0.54) | ALOX5L3MBTL1ALDH1A1TDP1HPGD | |
| SCHEMBL4161430 | 0.78 | MLYCD (0.68) | KMT2AALOX5L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL29318964 | 0.78 | ALDH1A1 (0.50) | KMT2AL3MBTL1ALDH1A1TDP1HPGD | |
| SCHEMBL4064688 | 0.77 | MLYCD (0.67) | KMT2AALOX5L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8392178 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | disclosed |