Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7936063 | 0.90 | MTNR1A (0.53) | CYP1A2CYP2A6ALDH1A1FLT3MTNR1A | |
| Acetic Acid SCHEMBL9228333 | 0.88 | MTNR1A (0.52) | CYP1A2CYP2A6ALDH1A1FLT3MTNR1A | |
| Acetic Acid SCHEMBL27085298 | 0.87 | MTNR1A (0.51) | CYP1A2CYP2A6FLT3MTNR1AMTNR1B | |
| Acetic Acid SCHEMBL9228337 | 0.87 | MTNR1A (0.51) | CYP1A2CYP2A6FLT3MTNR1AMTNR1B | |
| SCHEMBL22978760 | 0.87 | CYP1A2 (0.52) | CYP1A2CYP2A6ALDH1A1FLT3ACHE | |
| SCHEMBL13241099 | 0.85 | CYP1A2 (0.52) | CYP1A2CYP2A6ALDH1A1MAPTCYP11B1 | |
| SCHEMBL4203130 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1ACHEMTNR1A | |
| SCHEMBL13241108 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1ACHE | |
| SCHEMBL18813852 | 0.81 | LTA4H (0.51) | CYP1A2MAPTCYP11B1CYP11B2 | |
| SCHEMBL22259139 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP2A6ALDH1A1FLT3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556559-A | CLAVULANIC ACID ESTER, PENICILLIN | BEECHAM GROUP P.L.C. (GB) | 1985-12-03 | — | — | US | claimed |
| US-4428937-A | OXAPENICILLINS; BETA-LACTAMASE INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-01-31 | — | — | US | claimed |
| US-4427690-A | B-LACTAM ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1984-01-24 | — | — | US | claimed |
| EP-0002370-B1 | A PROCESS FOR THE PREPARATION OF ETHER DERIVATIVES OF CLAVULANIC ACID | BEECHAM GROUP PLC (GB) | 1983-05-11 | — | — | EP | claimed |
| EP-0002370-A1 | A process for the preparation of ether derivatives of clavulanic acid | BEECHAM GROUP PLC (GB) | 1979-06-13 | — | — | EP | claimed |
| US-4098897-A | ANTI BACTERIAL AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | claimed |
| JP-8268972-A | — | — | None | — | — | JP | disclosed |
| WO-2024109919-A1 | PYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛睿泽华医药科技（苏州）有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-115160098-B | Oxygen-containing compound deoxidization methylation method | 中国科学院兰州化学物理研究所 | 2023-06-06 | — | — | CN | disclosed |
| WO-2022271562-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| CN-115160098-A | Oxygen-containing compound deoxidation and methylation method | 中国科学院兰州化学物理研究所 | 2022-10-11 | — | — | CN | disclosed |
| US-10043978-B2 | Organic semiconductor formulations | FLEXTERRA, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-2952096-B1 | Amide compound, an arthropod pest control agent and a method for controlling arthropod pest | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-4297345-A | DEOXY- AND ISODEOXYCLAVULANIC ACID SYMERGISTIC WITH PENICILLIN AND CEPHALOSPORIN ANDITIOTICS | BEECHAM GROUP LIMITED (GB) | 1981-10-27 | — | — | US | disclosed |
| US-4232005-A | OXAPENICILLINS; SYNERGISTIC | BEECHAM GROUP LIMITED (GB) | 1980-11-04 | — | — | US | disclosed |
| EP-0002370-A1 | A process for the preparation of ether derivatives of clavulanic acid | BEECHAM GROUP PLC (GB) | 1979-06-13 | — | — | EP | disclosed |
| US-4140764-A | ISOCLAVULANIC ACID OR SALT, OXAPENICILLINS IN COMBINATION WITH PENCILLINS OR CEPHALOSPORINS | BEECHAM GROUP LIMITED (GB) | 1979-02-20 | — | — | US | disclosed |
| US-4123540-A | Isoclavulanic acid as an antibacterial and a β-lactamase inhibitor | BEECHAM GROUP LIMITED (GB) | 1978-10-31 | — | — | US | disclosed |
| US-4110165-A | CULTIVATION OF STREPTOMYCES CLAVULIGERIS | BEECHAM GROUP LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4098897-A | ANTI BACTERIAL AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |