Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27085298 | 0.97 | MTNR1A (0.51) | MTNR1AMTNR1BFLT3CYP1A2CYP2A6 | |
| Acetic Acid SCHEMBL7936063 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BFLT3CYP1A2CYP2A6 | |
| Acetic Acid SCHEMBL9228333 | 0.89 | MTNR1A (0.52) | MTNR1AMTNR1BFLT3CYP1A2CYP2A6 | |
| SCHEMBL5510892 | 0.87 | CYP1A2 (0.59) | MTNR1AMTNR1BFLT3CYP1A2CYP2A6 | |
| SCHEMBL10458013 | 0.80 | LMNA (0.54) | MTNR1AMTNR1BFLT3CYP1A2LMNA | |
| SCHEMBL9747620 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BCYP1A2CYP2A6CNR2 | |
| SCHEMBL23152686 | 0.76 | MTNR1A (0.46) | MTNR1AMTNR1BFLT3CYP1A2IDH1 | |
| SCHEMBL22978760 | 0.76 | CYP1A2 (0.52) | FLT3CYP1A2CYP2A6LMNAMAPT | |
| SCHEMBL13241099 | 0.74 | CYP1A2 (0.52) | CYP1A2CYP2A6MAPT | |
| SCHEMBL7099992 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BCYP1A2CYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645361-A1 | Production method for alkoxynaphthalenecarboxylic acid | SUMIKIN CHEMICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |