SCHEMBL5513657

SCHEMBL5513657

O=C(O)C(Oc1ccc[nH]1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.41
NAPRT Q6XQN6 1/20 0.38
GAA P10253 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
DAO P14920 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5510987 0.73 TSHR (0.37) NAPRTGAAKDM4EMAPTTSHR
SCHEMBL127155 0.72
SCHEMBL5515854 0.71 PPARG (0.37) NAPRTGAAKDM4EMAPTTSHR
SCHEMBL827013 0.70
SCHEMBL17223652 0.70 NAPRT (0.39) NAPRTGAAKDM4EMAPTTSHR
SCHEMBL28042296 0.69 SRD5A2 (0.36) KDM4ECYP2D6TSHRSMN1; SMN2
SCHEMBL5521676 0.69 TDP1 (0.42) NAPRTGAAKDM4EMAPTTSHR
SCHEMBL5511532 0.68 ALOX15 (0.50) GAAKDM4EMAPTTSHRRAB9A
SCHEMBL7207537 0.68 KDM4E (0.42) NAPRTGAAKDM4EMAPTCYP2D6
SCHEMBL2560281 0.67 LDHA (0.65) LDHAGAACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed